The 13-time Grand Slam title victor has now won 21 of his last 24 matches after a rollercoaster start to 2018 which saw him go 6-6.
"I thought I found pretty good accuracy and angles with the first serve, and also my second serve worked pretty well".
But while two of the sport's more popular players, No16 seed Nick Kyrgios and No10 seed David Goffin, made their exits in the first round, it was at the expense of two men who will ensure the crowds still pour in.
Nadal faces comeback hopeful Wawrinka in the third round after he came from behind to battle past Marton Fucsovics in two hours and 43 minutes.
Nadal, who lost to eventual champion Novak Djokovic in the Wimbledon semi-finals last month, beat former Grand Slam victor Wawrinka 7-5 7-6 (7-4) in Toronto.
Djokovic beat lucky loser Mirza Basic in straight sets last night after his original opponent Hyeon Chung pulled out just one hour before the match.
He is joined in the third round by the likes of Russia's Karen Khachanov, who following a rain delay completed a 6-4, 7-6 victory over last year's US Open semi-finalist Pablo Carreño Busta of Spain.
Earlier Wednesday, tournament officials announced that Juan Martin del Potro of Argentina had withdrawn because of a left wrist injury. I'm very pleased, I needed a match like this. Italy's Fabio Fognini, the No. 14 seed coming off a victory at Los Cabos, fell out with a 6-3, 7-5 (16-14) loss to Canada's Denis Shapovalov.
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German second seed Alexander Zverev, the victor last week in Washington, beat American Bradley Klahn 6-4 6-4 while fourth-seeded South African Kevin Anderson edged Russia's Evgeny Donskoy 4-6 6-2 7-6 (7-0). So now I'm going to use it in my favor for my next match against him and try to get the most out of it.
"I was waiting and I grabbed him like a bulldog and I stuck there", Tsitsipas said.
Toronto's Daniel Nestor - the oldest player at the tournament at 45 - and Vancouver's Vasek Pospisil lost to Feliciano and Marc Lopez 6-7 (8), 6-2, 10-6.
Djokovic was upstaged by Tsitsipas, who reached his seventh ATP Tour quarter-final of the season.
Pavlyuchenkova is leading 4-3 with the match due to resume tomorrow.
Elsewhere, five-time Grand Slam champion Maria Sharapova thrashed fellow Russian Daria Kasatkina 6-0, 6-2, while world number 43 Johanna Konta of Great Britain was leading two-time Grand Slam champion Victoria Azarenka of Belarus 6-3, 3-0 when their match was stopped by rain.
"I've had plenty of success in Toronto and Montreal, and I wanted to start off well", Djokovic said. Garcia came from behind to defeat Magdalena Rybarikova in three sets 4-6, 6-1, 6-3 on Tuesday.