Deschamps has a host of sparkling attacking talents within his squad, and there is a place for Chelsea's Olivier Giroud, but his former Arsenal teammate Alexandre Lacazette, Manchester United's Anthony Martial and Real Madrid's Karim Benzema are not amongst the names featuring in the French squad, who will head to Russian Federation as one of the tournament favourites.
Marseille's former West Ham midfielder Dimitri Payet was another big name to miss out.
Payet finally missed out his chance of shining in Russian Federation, as Deschamps feared a risk of relapse of the injury despite a three-week recovery.
Former Blackburn Rovers and Stoke City midfielder Steven N'Zonzi is included, while former Newcastle United forward Florian Thauvin and ex-Crystal Palace goalkeeper Steve Mandanda, who are both now at Marseille, also make the cut.
Manchester City full-back Benjamin Mendy is one of five Premier League players included, having only returned to action in April after almost seven months out with a knee injury.
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Antoine Griezmann will lead the attack, fresh from scoring twice for Atletico in the Europa League final.
Les Bleus have a wealth of options up front, with the likes of Antoine Griezmann, Kylian Mbappe, Ousmane Dembele and Chelsea's Olivier Giroud named in the squad.
Deschamps has until June 4 before submitting his definitive squad list.
France have been drawn in Group C at the World Cup, meaning they will face Australia, Peru and Denmark.