Noting that Assad should know that the use of chemical weapons will be met with a strong response, House Democratic Whip Steny H Hoyer said the USA acted with its allies to respond to the use of chemical weapons in violation of worldwide law.
The official added that "while the available information is much greater on the chlorine use, we do have significant information that also points to sarin use" in the attack.
Russian Foreign Ministry official Vladimir Ermakov struck a apparently conciliatory tone on Sunday, saying Washington would want to maintain a dialogue with Moscow about strategic stability after the raids, Russian media reported.
"I spoke to the president this morning and he said, "If the Syrian regime uses this poisonous gas again, the United States is locked and loaded", she said.
"The president used the term "mission accomplished" in the military sense".
"The evil and the despicable attack left mothers and fathers, infants and children thrashing in pain and gasping for air", he said.
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Russia denounced allegations of a gas attack in Douma and said it was staged by Britain to whip up anti-Russian hysteria. Russian Federation has vetoed at least six resolutions in the U.N. Security Council regarding chemical weapons.
Trump said a small American force over the past year has virtually eliminated Islamic State control over what once was a vast territory spanning parts of Syria and Iraq.
Western powers blamed President Bashar al-Assad, but Syria and its ally Russian Federation categorically denied the claims and accused the West of "fabricating" the incident to justify military action.
The Organisation for the Prohibition of Chemical Weapons was set to begin its investigation inside the Eastern Ghouta town of Douma on Saturday, just hours after the strikes.
McCain said the message to Assad must be that the cost of using chemical weapons is worse than any perceived benefit. "We must have a clear strategy for ending the conflict in Syria, and the Administration must articulate a clear plan to not just respond to this horrific chemical attack but to reach a lasting political solution in Syria: one that ends civilian casualties and ensures there is no permanent Iranian presence", he said.
Directly taunting US President Donald Trump, Assad said the effectiveness of Russia's weapons in repelling the strike proved whose military was really "lagging behind".
McKenzie said the Him Shinshar chemical-weapons storage facility near Homs was hit by 22 missiles.