Simon's resignation comes on the same day that Nassar - the disgraced doctor who treated athletes at Michigan State in addition to serving as team doctor for USA Gymnastics - was sentenced to 40-175 years in prison.
"Thank you to all the courageous victims who have continued to step forward", he said on Twitter.
Brian Breslin, chair of the university's board of trustees, issued a statement saying that it will accept Simon's resignation and that it was time for a change, per the State Journal.
Former Gov. Jennifer Granholm said in a Tweet that Simon acted in MSU's best interest by resigning.
When asked if President Simon would ever step down, Ferguson said, "That will not happen, period".
He says Michigan State University failed the victims in the most despicable way but he believed it wasn't appropriate for the legislature to intervene. More than 150 women alleged assault at the hands of Nassar. Therefore, I am tendering my resignation as president according to the terms of my employment agreement.
Kardashian-Jenner sisters front new Calvin Klein ads
Kylie Jenner has been in hiding since rumors circulated that she's pregnant with Travis Scott's baby. Kylie sent an arrangement of roses in the shape of a heart to Kim .
"President Simon has served with distinction as MSU's president for 13 years and has been a constant presence at the university for more than 40 years", Breslin said.
As tragedies are politicized, blame is inevitable.
"Under Dr. Simon's leadership, Spartans of yesterday and today have benefitted in more ways than one and the many opportunities in and outside of the classroom that have been provided", wrote Lorenzo Santavicca.
An investigation revealed that Nassar's abuse at Michigan State dates back as far as 1997 when then 16-year-old Larissa Boyce told a gymnastics coach at the school about Nassar's abuse, a report that was never filed.
"Thank you fellow survivors for your courage, strength, and leadership, you have all had an overwhelming impact on me and I am proud to stand with you all". "As president, it is only natural that I am the focus of this anger", Lou Anna Simon said in a resignation letter.