The evening began with the normally colorful red carpet transformed into a sea of black gowns as actresses showed solidarity with victims of sexual harassment inside and outside the entertainment industry.
The movie, in which downtown Sylva stands in for the fictional Ebbing, won the Globe for Best Motion Picture (Drama) as well as Best Screenplay, for writer-director Martin McDonagh; Best Actress (Drama), for Frances McDormand; and Best Supporting Actor, for Sam Rockwell.
But it could be argued the night belonged to Oprah Winfrey, who was the receipient of the Cecil B. De Mille award.
"But their time is up", she added, earning a standing ovation."I want all the girls watching here and now to know that a new day is on the horizon", she added.
The actress then joked that while she's thankful for the HFPA, she is unsure on who they truly are. Presenting the Best Actor in a Drama award, Geena Davis said that the victor would give "half of their salary back so that women can make more than them".
-Actress, Drama: Elisabeth Moss, "The Handmaid's Tale". Alexander Skarsgard and Laura Dern both took home the awards for Best Supporting Actor and Actress in a TV Series, Miniseries, or TV Movie, respectively.
McDormand was again bleeped when she spoke of the "tectonic shift" in Hollywood that has seen the treatment of women thrust into the spotlight.
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Weber ( 500 Days of Summer, The Spectacular Now ) at Sunday's Golden Globe Awards (watch above). Sheedy featured in the 2014 Broadway production The Long Shrift , which was directed by Franco.
-Actress, Series, Musical or Comedy: Rachel Brosnahan, "The Marvelous Mrs. Maisel".
While it was a big night for streaming video companies, HBO - which has its own, popular subscription-based streaming service - also won big at the ceremony.
-Actor, Series, Musical or Comedy: Aziz Ansari, "Master of None".
Sterling K. Brown was the only television network actor to take home a Globe, earning the prize for drama series actor for his work in NBC's "This is Us".
Awarding the Best Actress in a Comedy trophy, Jessica Chastain said, "The victor will receive the 25 percent of her salary that went missing in the wage gap".
"Time is up", she said. "I'm especially proud and inspired by all the women who felt strong enough and empowered enough to speak up and share their personal stories.This year, we became the story". When the orchestra tried to play him offstage, he hushed the conductor and continued saying, "For 25 years, I have handcrafted very odd little tales made of motion, color, light, and shadow".